How socially acceptable are drugs in America?

I used to live in America as a kid in the noughties and it seemed that even "soft drugs" like cannabis still had a taboo whenever a discussion came up. When I went back to work in the summer, it seems that many people's attitudes have changed especially with many States legalising cannabis.

I wonder if people have the same relaxed attitude towards the recreation use of other drugs like cocaine, opioids, or amphetamines.